The pathways listed below are relevant to cancer pathophysiology and treatment. Each hyperlinked pathway includes, where relevant, a description, upstream pathways, downstream pathways, diseases in which pathway is aberrantly activated, therapies that target the pathway, genes involved in the pathway, and a simplified figure highlighting the most cancer-relevant proteins and therapies. 

Pathway Color

Contributors: Christine M. Lovly, M.D., Ph.D.

Suggested Citation: Lovly, C. 2016. Pathways. My Cancer Genome (Updated May 24).

Last Updated: May 24, 2016

Disclaimer: The information presented at is compiled from sources believed to be reliable. Extensive efforts have been made to make this information as accurate and as up-to-date as possible. However, the accuracy and completeness of this information cannot be guaranteed. Despite our best efforts, this information may contain typographical errors and omissions. The contents are to be used only as a guide, and health care providers should employ sound clinical judgment in interpreting this information for individual patient care.