Genes

XBP1

X-box binding protein 1 (XBP1) is a gene that encodes a transcription factor protein that functions in the regulation of MHC class II genes. The protein may also be involved in upregulating the expression of viral proteins. Missense mutations, nonsense mutations, silent mutations, frameshift deletions and insertions, and in-frame deletions are observed in cancers such as biliary tract cancer, intestinal cancer, and stomach cancer.

Modified: July 1, 2015

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