Tropomyosin 4 (TPM4) is a gene that encodes a protein that functions in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. The protein also provides stability to actin filaments and regulates the access of other actin-binding proteins. Fusions, missense mutations, and silent mutations are observed in cancers such as breast cancer and intestinal cancer.

Modified: July 1, 2015

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