Genes

TNK2

Tyrosine kinase, non-receptor, 2 (TNK2) is a gene that encodes a protein that inhibits the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. Missense mutations, silent mutations, frameshift deletions, nonsense mutations, and frameshift insertions are observed in cancers such as colon cancer, skin cancer, and eye cancer.

Modified: August 28, 2015

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