Tumor necrosis factor receptor superfamily, member 14 (TNFRSF14) is a gene that encodes a protein that belongs to the tumor necrosis factor (TNF) superfamily. The protein functions in the activation of inflammatory and inhibitory T-cell immune responses. Missense mutations, nonsense mutations, frameshift deletions and insertions, and in-frame insertions are observed in cancers such as hematopoietic and lymphoid cancers and kidney cancer.

Modified: July 1, 2015

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