Genes

TCF7L2

Transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2) is a gene that encodes a transcription factor protein that is involved in the WNT signaling pathway. The protein functions in blood glucose homeostasis. Fusions, missense mutations, nonsense mutations, silent mutations, frameshift deletions and insertions, and in-frame deletions are observed in cancers such as fallopian tube cancer, intestinal cancer, and stomach cancer.

 

Modified: July 1, 2015

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