Succinate-CoA ligase, ADP-forming, beta subunit (SUCLA2) is a gene that encodes a protein
that functions as a mitochondrial matrix enzyme. The protein
is an ATP-specific beta subunit that dimerizes with an alpha subunit to participate in the TCA
cycle. Missense mutations, nonsense mutations, silent mutations, and frameshift deletions are observed in cancers
such as endometrial cancer, intestinal cancer, and skin cancer.
December 4, 2015
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