SRY (sex determining region y)-box 2 (SOX2) is a gene
that encodes a transcription factor protein that is a member of the SOX family.
The protein functions in the regulation of
embryonic development and stem-cell maintenance in the central nervous system. Missense mutations and silent mutations are observed in cancers such as cervical cancer,
endometrial cancer, and intestinal cancer.
July 1, 2015
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