Genes

SOCS3

Suppressor of cytokine signaling 3 (SOCS3) is a gene that encodes a protein that functions as a negative regulator of cytokine signaling. The protein is also involved in the inhibition of JAK2 kinase activity. Missense mutations, silent mutations, and frameshift deletions are observed in cancers such as intestinal cancer, skin cancer, and stomach cancer.

Modified: July 1, 2015

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