Succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD) is a gene that encodes a protein that functions as a component of the respiratory chain and is involved in the oxidation of succinate. The protein anchors the complex to the matrix side of the inner mitochondrial membrane. Missense mutations, nonsense mutations, silent mutations, and nonstop extensions are observed in cancers such as endometrial cancer, intestinal cancer, and stomach cancer.

Modified: July 1, 2015

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