Genes

RRM1

Ribonucleotide reductase M1 (RRM1) is a gene that encodes a subunit of ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. Missense mutations, silent mutations, nonsense mutations, and inframe deletions are observed in cancers such as colon cancer, skin cancer, and esophageal cancer.

Modified: August 27, 2015

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