Ras-like without CAAX 1 (RIT1) is a gene that encodes a protein that belongs to the Ras-related GTPases subfamily. The protein regulates p38 MAPK-dependent signaling cascades that are related to cellular stress. Missense mutations, nonsense mutations, silent mutations, and in-frame deletions are observed in cancers such as intestinal cancer, lung cancer, and salivary gland cancer.

Modified: July 1, 2015

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