Genes

RAF1

Raf-1 proto-oncogene, serine/threonine kinase (RAF1, also known as CRAF) is a gene that encodes a protein that functions downstream of RAS and activates MEK1 and MEK2. Fusions, rearrangements, missense mutations, nonsense mutations, and silent mutations are observed in cancers such as endometrial cancer, intestinal cancer, and stomach cancer.

Related Pathways

Modified: December 4, 2015

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