Genes

PTK7

Protein tyrosine kinase 7 (inactive) (PTK7) is a gene that encodes a receptor protein tyrosine kinase that does not have catalytic tyrosine kinase activity. The protein functions in the Wnt signaling pathway and cell processes such as polarity and adhesion. Fusions, missense mutations, nonsense mutations, silent mutations, and frameshift deletions and insertions are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.

Modified: July 1, 2015

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