Genes

PRKDC

Protein kinase, DNA-activated, catalytic polypeptide (PRKDC) is a gene that encodes a protein that functions as the catalytic subunit of the DNA-dependent protein kinase. The protein also plays important roles in DNA double strand break repair and recombination. Missense mutations, nonsense mutations, silent mutations, frameshift deletions and insertions, and in-frame deletions are observed in cancers such as endometrial cancer, intestinal cancer, and stomach cancer.

Modified: July 1, 2015

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