Protein kinase C, iota (PRKCI) is a gene that encodes a serine/threonine protein kinase that plays a role in microtubule dynamics in the early secretory pathway. Missense mutations, synonymous mutations, frameshift deletions, frameshift insertions, and nonsense mutations are observed in cancers such as colon cancer, skin cancer, and salivary gland cancer.

Modified: January 7, 2016

Disclaimer: The information presented at is compiled from sources believed to be reliable. Extensive efforts have been made to make this information as accurate and as up-to-date as possible. However, the accuracy and completeness of this information cannot be guaranteed. Despite our best efforts, this information may contain typographical errors and omissions. The contents are to be used only as a guide, and health care providers should employ sound clinical judgment in interpreting this information for individual patient care.