Genes

PPP1CB

Protein phosphatase 1, catalytic subunit, beta isozyme (PPP1CB) is a gene that encodes a protein that functions as a catalytic subunit of protein phosphatase 1 (PP1). PP1 regulates cellular processes such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Fusions, missense mutations, nonsense mutations, silent mutations, nonstop extensions, and frameshift insertions are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.

Modified: July 1, 2015

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