Pim-1 proto-oncogene, serine/threonine kinase (PIM1) is a gene that encodes a protein that functions as a serine/threonine kinase. The protein perpetuates signal transduction in blood cells and contributes to cell proliferation and survival. Fusions, missense mutations, nonsense mutations, silent mutations, and in-frame deletions are observed in cancers such as hematopoietic and lymphoid cancers, intestinal cancer, and skin cancer.

Modified: July 1, 2015

Disclaimer: The information presented at is compiled from sources believed to be reliable. Extensive efforts have been made to make this information as accurate and as up-to-date as possible. However, the accuracy and completeness of this information cannot be guaranteed. Despite our best efforts, this information may contain typographical errors and omissions. The contents are to be used only as a guide, and health care providers should employ sound clinical judgment in interpreting this information for individual patient care.