Genes

PIM1

Pim-1 proto-oncogene, serine/threonine kinase (PIM1) is a gene that encodes a protein that functions as a serine/threonine kinase. The protein perpetuates signal transduction in blood cells and contributes to cell proliferation and survival. Fusions, missense mutations, nonsense mutations, silent mutations, and in-frame deletions are observed in cancers such as hematopoietic and lymphoid cancers, intestinal cancer, and skin cancer.

Modified: July 1, 2015

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