Phosphatidylinositol binding clathrin assembly protein (PICALM) is a gene that encodes a protein that functions as a clathrin assembly protein. The protein may also regulate the size of the clathrin cage to control the amount of membrane recycled. Fusions, missense mutations, nonsense mutations, and silent mutations are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.

Modified: July 1, 2015

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