Genes

PDPK1

3-phosphoinositide dependent protein kinase 1 (PDPK1) is a gene that encodes a protein that functions as a serine/threonine kinase. The protein is involved in signal transduction from insulin and regulates proliferation, survival, and growth of pancreatic cells. Missense mutations, silent mutations, and frameshift deletions and insertions are observed in cancers such as cancers of the biliary tract, intestinal cancer, and stomach cancer.

Modified: July 1, 2015

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