Genes

PASK

PAS domain containing serine/threonine kinase (PASK) is a gene that encodes a protein that functions as a serine/threonine kinase. The protein is important for protein translation and energy homeostasis. The protein is also involved in the regulation of glycogen synthase synthesis, glucose stimulated insulin production, and glucagon secretion. Missense mutations, nonsense mutations, silent mutations, and frameshift deletions are observed in cancers such as intestinal cancer, skin cancer, and stomach cancer.

Modified: July 1, 2015

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