Genes

PARK2

Parkin RBR E3 ubiquitin protein ligase (PARK2) is a gene that encodes a protein that is a member of a multiprotein E3 ubiquitin ligase complex that functions in mediating the targeting of proteins for proteasomal degradation. Missense mutations, nonsense mutations, silent mutations, and frameshift deletions and insertions are observed in cancers such as intestinal cancer, skin cancer, and stomach cancer.

Related Pathways

Modified: December 4, 2015

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