Genes

PAK4

p21 protein (Cdc-42/Rac)-activated kinase 4 (PAK4) is a gene that encodes a protein that functions as a serine/threonine p21-activating kinase. The protein is involved in linking Rho GTPases to cytoskeleton reorganization and nuclear signaling and also functions as a target for small GTP binding proteins. Missense mutations, nonsense mutations, silent mutations, frameshift deletions, and in-frame deletions are observed in cancers such as intestinal cancer, skin cancer, and stomach cancer.

Modified: July 1, 2015

Disclaimer: The information presented at padiracinnovation.org is compiled from sources believed to be reliable. Extensive efforts have been made to make this information as accurate and as up-to-date as possible. However, the accuracy and completeness of this information cannot be guaranteed. Despite our best efforts, this information may contain typographical errors and omissions. The contents are to be used only as a guide, and health care providers should employ sound clinical judgment in interpreting this information for individual patient care.