Neurotrophic tyrosine kinase, receptor, type 3 (NTRK3) is a gene that encodes a protein that belongs to the neurotrophic tyrosine kinase (NTRK) family. The protein functions in the phosphorylation of members of the MAP kinase pathway, cell differentiation, and the development of proprioceptive neurons. Fusions, missense mutations, nonsense mutations, silent mutations, and frameshift deletions are observed in cancers such as intestinal cancer, lung cancer, and skin cancer.

Related Pathways

Modified: December 4, 2015

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