Genes

NFKB2

Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2) is a gene that encodes a protein that functions as a subunit of the transcription factor complex nuclear factor-kappa-B. The protein activates genes that participate in inflammation and immunity. Fusions, missense mutations, nonsense mutations, silent mutations, frameshift deletions, and in-frame deletions are observed in cancers such as bone cancer, endometrial cancer, and skin cancer.

Modified: July 1, 2015

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