Genes

MYC

The v-myc avian myelocytomatosis viral oncogene homolog (MYC) gene encodes a nuclear phosphoprotein that functions in cell cycle progression, apoptosis, and cellular transformation. The protein also functions as a transcription factor that controls gene expression. Missense mutations, silent mutations, frameshift deletions, and in-frame deletions are observed in cancers such as endometrial cancer, hematopoietic and lymphoid cancers, and stomach cancer.

Modified: July 1, 2015

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