Genes

MLLT4

Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog; Drosophila); translocated to, 4 (MLLT4; also known as AF6) is a gene that encodes a nectin- and actin-filament binding protein that functions as a component of an adhesion system and connects nectin to the actin cytoskeleton. Fusions, missense mutations, nonsense mutations, silent mutations, frameshift deletions and insertions, and in-frame deletions are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.

Modified: July 1, 2015

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