Genes

MLLT1

Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog; Drosophila); translocated to, 1 (MLLT1; also known as ENL) is a gene that encodes a protein that functions as a component of the super elongation complex (SEC). This complex facilitates the increase in the catalytic rate of RNA polymerase II. Fusions, missense mutations, nonsense mutations, silent mutations, frameshift deletions, and in-frame deletions are observed in cancers such as eye cancer, intestinal cancer, and skin cancer.

Modified: July 1, 2015

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