Genes

MDM2

MDM2 proto-oncogene, E3 ubiquitin protein ligase (MDM2) is a gene that encodes a protein that functions as a nuclear-localized E3 ubiquitin ligase. Missense mutations, silent mutations, frameshift deletions, and in-frame deletions are observed in cancers such as endometrial cancer, intestinal cancer, and stomach cancer.

Related Pathways

Modified: December 4, 2015

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