Genes

MAP2K2

Mitogen-activated protein kinase kinase 2 (MAP2K2) is a gene that encodes a protein that is a member of the MAP kinase kinase family. The protein functions as a dual specificity protein kinase that regulates mitogen growth factor signal transduction by phosphorylating and activating MAPK1/ERK2 and MAPK2/ERK3. Missense and silent mutations are observed in cancers such as bone cancer, skin cancer, and stomach cancer.

Related Pathways

Modified: December 4, 2015

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