Mago-nashi homolog, proliferation-associated (Drosophila) (MAGOH) is a gene that encodes a protein that is the mammalian homolog to the Drosophila mago nashi. In Drosophila, the protein functions in germplasm assembly and germline development. In the human homolog, the function is similar; however, in mammals, mRNA expression is expressed throughout adult tissues, rather than limited to the germplasm. Missense and silent mutations are observed in cancers such as endometrial cancer, cancers of the upper aerodigestive tract, and cancers of the urinary tract.

Modified: July 1, 2015

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