Lysine (K)-specific demethylase 6A (KDM6A) is a gene that encodes a protein that functions in the catalysis of the demethylation of tri/dimethylated histone H3. Missense mutations, nonsense mutations, silent mutations, whole gene deletions, frameshift deletions and insertions, and in-frame deletions and insertions are observed in cancers such as parathyroid cancer, salivary gland cancer, and cancers of the urinary tract.

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Modified: December 4, 2015

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