Genes

IRS1

Insulin receptor substrate 1 (IRS1) is a gene that encodes a protein that is phosphorylated by insulin receptor tyrosine kinase. The protein is important for insulin regulation. Missense mutations, nonsense mutations, silent mutations, frameshift deletions and insertions, and in-frame deletions are observed in cancers such as intestinal cancer, lung cancer, and stomach cancer.

Modified: July 1, 2015

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