Genes

INPP5D

Inositol polyphosphate-5-phosphatase (INPP5D) is a gene that encodes a protein that utilizes hydrolysis of the 5’ phosphate from phosphatidylinositol (3, 4, 5)-triphosphate and inositol-1, 3, 4, 5-tetrakisphosphate to alter/affect cell signaling pathways. Specifically, the protein may function in nuclear inositol phosphate signaling. Missense mutations, nonsense mutations, silent mutations, frameshift deletions, and in-frame deletions are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.

Modified: July 1, 2015

Disclaimer: The information presented at padiracinnovation.org is compiled from sources believed to be reliable. Extensive efforts have been made to make this information as accurate and as up-to-date as possible. However, the accuracy and completeness of this information cannot be guaranteed. Despite our best efforts, this information may contain typographical errors and omissions. The contents are to be used only as a guide, and health care providers should employ sound clinical judgment in interpreting this information for individual patient care.