IKAROS family zinc finger 2 (Helios) (IKZF2) is a gene
that encodes a protein that functions as a
hematopoietic-specific transcription factor
that regulates lymphocyte development. Importantly, the protein
is thought to function in early hematopoietic development. Missense mutations, nonsense mutations,
silent mutations, and frameshift deletions and
insertions are observed in cancers such as genital tract cancer, intestinal cancer, and skin
July 1, 2015
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