Insulin-like growth factor 2 receptor (IGF2R) is a gene that encodes a protein that functions in the intracellular transport of lysosomal enzymes, activation of transforming growth factor beta, and degradation of insulin-like growth factor 2. Missense mutations, silent mutations, nonsense mutations, frameshift deletions, frameshift insertions, and in-frame deletions are observed in cancers such as colon cancer, endometrial cancer, and stomach cancer.

Modified: August 27, 2015

Disclaimer: The information presented at is compiled from sources believed to be reliable. Extensive efforts have been made to make this information as accurate and as up-to-date as possible. However, the accuracy and completeness of this information cannot be guaranteed. Despite our best efforts, this information may contain typographical errors and omissions. The contents are to be used only as a guide, and health care providers should employ sound clinical judgment in interpreting this information for individual patient care.