Homeobox A11 (HOXA11) is a gene that encodes a transcription factor protein that functions in the regulation of gene expression, morphogenesis, and differentiation. The protein also regulates uterine development that is necessary for female fertility. Fusions, nonsense mutations, missense mutations, silent mutations, frameshift deletions, and in-frame deletions are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.

Modified: July 1, 2015

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