Histone cluster 1, H2bj (HIST1H2BJ) is a gene that encodes a protein that functions as a core component of the nucleosome. The protein plays an important role in transcriptional regulation, DNA replication, and chromosomal stability. Missense mutations, silent mutations, nonstop extensions, and in-frame deletions are observed in cancers such as prostate cancer, skin cancer, and stomach cancer.

Modified: July 1, 2015

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