Genes

FOXO3

Forkhead box O3 (FOXO3) is a gene that encodes a protein that functions as a transcriptional activator. The protein transcriptionally initiates apoptosis in the absence of survival factors. Fusions, missense mutations, silent mutations, and frameshift deletions and insertions are observed in cancers such as intestinal cancer, skin cancer, and stomach cancer.

Modified: July 1, 2015

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