Genes

FASLG

Fas ligand (TNF superfamily, member 6) (FASLG) is a gene that encodes a protein that belongs to the tumor necrosis factor superfamily. The protein functions in the induction of apoptosis by binding to FAS. The binding of FASLG to FAS is important for cellular processes such immune regulation. Missense mutations, silent mutations, nonstop extensions, and frameshift deletions and insertions are observed in cancers such as endometrial cancer, intestinal cancer, and skin cancer.

Related Pathways

Modified: December 4, 2015

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