Fas cell surface death receptor (FAS)
is a gene that encodes a protein that belongs to the TNF-receptor superfamily. The protein
functions in the physiological regulation of programmed cell death (apoptosis). The protein also
plays a role in various diseases and malignancies of the immune system. Missense mutations,
nonsense mutations, silent mutations, and frameshift deletions are observed in cancers such as
endometrial cancer, hematopoietic and lymphoid cancers, and skin cancer.
December 4, 2015
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