Exostosin glycosyltransferase 1 (EXT1) is a gene that encodes a protein that is involved in the chain elongation step of heparan sulfate biosynthesis. Missense mutations, silent mutations, nonsense mutations, frameshift deletions, and in-frame deletions are observed in cancers such as stomach cancer, colon cancer, and endometrial cancer.

Modified: August 27, 2015

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