The gene ets variant 6 (ETV6) encodes for an ETS family transcription factor (Gene 2014). ETV6 is a
DNA-binding protein involved in transcription regulation during embryonic development and
hematopoiesis (Gene 2014; Genetics Home Reference 2014).
ETV6 variants—rearrangements, in particular—have been observed in myelodysplastic
syndromes, other hematologic malignancies, and sarcomas.
Strickland, S.A., Kim, A.S. 2014.
My Cancer Genome
(Updated September 2014)
September 23, 2014
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