Genes

ETS1

V-ets avian erythroblastosis virus E26 oncogene homolog 1 (ETS1) is a gene that encodes a transcription factor protein that functions as either a transcriptional activator or repressor of multiple genes. The protein is also plays a role in stem cell development, cell senescence and death, and tumorigenesis. Fusions, missense mutations, nonsense mutations, silent mutations, and frameshift deletions are observed in cancers such as endometrial cancer, intestinal cancer, and pleural cancer.

Modified: July 1, 2015

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