The EPH receptor A2 (EPHA2) gene is a member of the protein-tyrosine kinase subfamily of ephrin receptors and encodes a protein that associates with ephrin-A ligands. Missense mutations, nonsense mutations, silent mutations, and EPHA2 overexpression are observed in cancers such as biliary tract cancers, skin cancer, and stomach cancer.

Modified: July 1, 2015

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