Genes

ELF4

E74-like factor 4 (ets domain transcription factor) (ELF4) is a gene that encodes a protein that functions as a transcriptional activator. The protein binds and activates the promoters of the CSF2, IL3, IL8, and PRF1 genes. Fusions, missense mutations, nonsense mutations, silent mutations, and frameshift deletions are observed in cancers such as intestinal cancer, skin cancer, and stomach cancer.

Modified: July 1, 2015

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