Eukaryotic translation initiation factor 4A2 (EIF4A2) is a gene that encodes a protein that functions as an ATP-dependent RNA helicase that plays a role in cap recognition and is required for mRNA binding to the ribosome. Fusions, missense mutations, nonsense mutations, silent mutations, frameshift deletions, and in-frame deletions are observed in cancers such as breast cancer, endometrial cancer, and skin cancer.

Modified: July 1, 2015

Disclaimer: The information presented at is compiled from sources believed to be reliable. Extensive efforts have been made to make this information as accurate and as up-to-date as possible. However, the accuracy and completeness of this information cannot be guaranteed. Despite our best efforts, this information may contain typographical errors and omissions. The contents are to be used only as a guide, and health care providers should employ sound clinical judgment in interpreting this information for individual patient care.