Genes

DUSP4

Dual specificity phosphatase 4 (DUSP4) is a gene that encodes a protein that belongs to the dual specificity protein phosphatase subfamily. The protein functions in the negative regulation of members of the mitogen-activated protein kinase family. The inactivation of these kinases is achieved by dephosphorylation. Fusions, missense mutations, silent mutations, nonstop extensions, and frameshift insertions are observed in cancers such as intestinal cancer, skin cancer, and stomach cancer.

Modified: July 1, 2015

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