Dual specificity phosphatase 2 (DUSP2) is a gene that encodes a protein that belongs to the dual specificity protein phosphatase subfamily. The protein inactivates target kinases via dephosphorylation of phosphoserine/threonine and phosphotyrosine residues. The protein also functions in the negative regulation of the MAP kinase superfamily. Missense mutations, silent mutations, frameshift insertions and deletions, and in-frame deletions are observed in cancers such as breast cancer, lung cancer, and skin cancer.

Modified: July 1, 2015

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