Dual specificity phosphatase 2 (DUSP2) is a gene
that encodes a protein that belongs to the
dual specificity protein phosphatase
subfamily. The protein inactivates target
kinases via dephosphorylation of
phosphoserine/threonine and phosphotyrosine residues. The protein
also functions in the negative regulation of the MAP kinase
superfamily. Missense mutations, silent mutations, frameshift insertions and
deletions, and in-frame deletions are observed in cancers such as breast cancer, lung cancer,
and skin cancer.
July 1, 2015
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