DOT1-like histone H3K79 methyltransferase (DOT1L) is a gene that encodes a protein
that functions as a histone meythltransferase that methylates lysine-79 of histone H3. Missense
mutations, nonsense mutations, silent mutations,
frameshift insertions, and in-frame deletions are observed in cancers such as intestinal cancer,
stomach cancer, and cancers of the urinary tract.
December 4, 2015
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